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- W2365964897 abstract "Objective To explore the effect of atorvastatin combined with valsartan on inflammatory factors in patients w ith chronic nephritis.Methods 116 patients w ith chronic nephritis were randomly divided into control group(n =52) and experience group(n =64).The two groups were given routine treatment.Control group received enalapril orally and experience group were given atorvastatin combined w ith valsartan therapy.The treatment course of the 2 groups was 24 w eeks.Urine protein,renal function,blood lipid and inflammatory factors were compared before and after treatment betw een the tw o groups.Results After treatment,the 24-hour urine protein excretion,β2-M G,SCr and BUN in experience group were much low er than those in control group(P 0.05);TC and LDL-C in experience group w ere less than those in control group(P 0.05);There was no significant difference of TG and HDL-C betw een the tw o groups(P 0.05).The serum hs-CRP,TNF-α and IL-6 level after treatment greatly were decreased more significantly than these of control group(P 0.05).Conclusion Atorvastatin combined with valsartan therapy for chronic nephritis can greatly decrease urine protein and inflammatory factors,and it is beneficial to protect renal function." @default.
- W2365964897 created "2016-06-24" @default.
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- W2365964897 date "2013-01-01" @default.
- W2365964897 modified "2023-09-23" @default.
- W2365964897 title "Effect of atorvastatin combined with valsartan on inflammatory factors in patients with chronic nephritis" @default.
- W2365964897 hasPublicationYear "2013" @default.
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