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- W2366000364 abstract "Objective:To observe the immune disorder and anti-hematopoeitic factor level in aplastic anemia mice,and the effect of Liang-xue-jie-du decoction on them.Methods:We duplicate aplastic anemia mice model by chemophysical method,administrate Liang-xue-jie-du decoction on them,and analyze the full blood count,reticular cell count,apoptosis of marrow hemotopoietic stem cell and T cell,and the level of anti-hematopoietic factor in marrow.Results:The model mice showed the full blood count,reticular cell count are decreased,T cell in bone marrow is increased and apoptosis is suppressed,which lead to up-regulation of anti-hematopoietic factor and in turn promote the apoptosis of hematopoietic stem cell.Liang-xue-jie-du decoction can partly reverse these effect and improve the full blood count,reticular cell count.Conclusion:Liang-xue-jie-du decoction can adjust the unbalance between apoptosis of bone marrow T cell and hematopoietic stem cell,reduce the anti-hematopoietic factor,which suggest heat toxity in TCM is correlated with cell immune disorder." @default.
- W2366000364 created "2016-06-24" @default.
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- W2366000364 date "2009-01-01" @default.
- W2366000364 modified "2023-09-24" @default.
- W2366000364 title "Liang-xue-jie-du Decoction Adjust the Marrow Immune-disorder in Aplastic Anemia Mouse" @default.
- W2366000364 hasPublicationYear "2009" @default.
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