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- W2366003411 abstract "Objectives To evaluate the peripheral levels of testosterone, free testosterone, soluble intercellular adhesion molecule-1(sICAM-1), and association between them in patients with different type of coronary heart disease, further more to understand the role they played in the pathogenesis of male acute coronary syndrome(ACS). Methods For measuring serum concentrations of testosterone, free testosterone,and sICAM-1, three groups of 30 patients with acute myocardial infarction (AMI), unstable angina pectoris (UAP),stable angina pectoris(SAP) and one equivalent group of 30 healthy volunteers(control group) were recruited. The serum levels of testosterone, free testosterone and sICAM-1 were measured with ELISA method. Results (1)The serum level of free testosterone in the patients with ACS was significantly lower, but of sICAM-1 was notably higher than those in the control group (P0.01). (2)Significantly negative correlation between the serum levels of free testosterone and sICAM-1 was observed in the patients with ACS (P0.01). Conclusions The alteration of serum concentrations of free testosterone and sICAM-1 are associated with initiation and progression of ACS, and they may help evaluating stability of coronary atherosclerotic score and severity of disease. In addition, this study hints a new way to prevent and treat ACS." @default.
- W2366003411 created "2016-06-24" @default.
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- W2366003411 date "2006-01-01" @default.
- W2366003411 modified "2023-09-27" @default.
- W2366003411 title "Correlation between the serum levels of testosterone and sICAM-1 in male patients with acute coronary syndrome" @default.
- W2366003411 hasPublicationYear "2006" @default.
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