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- W2366055294 abstract "Objective:To establish a capillary electrochromatography method for separation of cetirizine enanti- omers,and using cationic surfactant and chiral selector of norvancomycin hydrochloride as running buffer.Methods: The effects of pH and the concentrations of norvancomycin hydrochloride and Tris on chiral resolution were exam- ined and separation conditions were optimized.Results:It was observed that a good separation of enantiomers for ce- tirizine could be achieved in 25 mmol·L~(-1) Tris-H_3PO_4 buffer system(pH 4.5)containing 1.0 mmol·L~(-1) nor- vancomycin and 0.04 g·L~(-1) tetrabutyl ammonium iodide.The resolution between R-cetirizine and S-cetirizine was 1.8.Conclusion:The method can separate enantiomers for cetirizine." @default.
- W2366055294 created "2016-06-24" @default.
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- W2366055294 date "2007-01-01" @default.
- W2366055294 modified "2023-09-23" @default.
- W2366055294 title "Chiral resolution of cetirizine by capillary electrochromatography using norvancomycin hydrochloride as chiral selector" @default.
- W2366055294 hasPublicationYear "2007" @default.
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