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- W2366132442 abstract "Objective:To investigate the expression of MRP1/CD9 as well as their correlations with the metastasis of colorectal carcinoma.Methods:Tissue microarray and immunohistochemistry were used to detect the expression of MRP1/CD9 in 244 cases of colorectal carcinoma.Results:The positive rate of MRP1/CD9 expression was 77.9% in colorectal carcinoma.The expression of MRP1/CD9 had no relationship with the patients' sex,age,and the depth of infiltration,but it had relationships with the differentiated degree,Dukes stages,and lymphnode metastasis.The expression of MRP1/CD9 was higher in colorectal carcinomas with moderate or high differention than that in the ones with poor differention.The expression of MRP1/CD9 was higher in colorectal carcinomas with Dukes A+B stages than that in the ones with Dukes C+D stages.The expression of MRP1/CD9 was higher in colorectal carcinomas without lymphnode metastasis than that in the ones with lymphnode metastasis.Above all had the significant meaning(P 0.05).Forward stepwise binary logistic regression reveals:differentiation,which went into the equation first,is the significant factor of MRP1/CD9 expression.The expression of MRP1/CD9 was negatively related to Dukes stages in monofactoral analysis,but disappearing in multifactoral analysis.Conclusion:The loss expression of MRP1/CD9 are closed correlated with the metastasis of colorectal carcinoma,and this marker has hopes to become a new target to evaluate the tumor prognosis." @default.
- W2366132442 created "2016-06-24" @default.
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- W2366132442 date "2012-01-01" @default.
- W2366132442 modified "2023-09-23" @default.
- W2366132442 title "Detecting of MRP1/CD9 in colorectal carcinoma using tissue microarrays" @default.
- W2366132442 hasPublicationYear "2012" @default.
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