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- W2366162079 abstract "Objective To investigate the ralationship between diabetes and somatostatin(SOM).Methods We established a streptozocin-induced diabetic rats model and stutied the changes of SOM mRNA in hippocampi of diabetic and normal rats by using in situ hybridication and computer image analysis.We studied the machanism of chronic diabetes encephalopathy by observing the changes of somatoostatin mRNA in the hippocampus of diabetic rats was.Results The number,light density and average area of positive cells in dentate gyrus area of hippocampus in diabetes model were reduced significantly as compared with normal rats (P0 01).Conclusion A decline in SOM mRNA expression may play a role in chronic diabetes encephalopathy." @default.
- W2366162079 created "2016-06-24" @default.
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- W2366162079 date "2004-01-01" @default.
- W2366162079 modified "2023-09-24" @default.
- W2366162079 title "Research on Changes of Diabetic Rats Hippocampus Somatostatin mRNA and Cognition Ability" @default.
- W2366162079 hasPublicationYear "2004" @default.
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