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- W2366169401 abstract "This experiment was conducted to study the age-related changes in the lymphocyte proliferation and apoptosis during the embryonic and post embryonic development of the Tianfu duck thymus.Sixty five Tianfu ducks were divided into 13groups as follows:22,24and 26days embryonic stage,and 0(neonatal stage),3,5,8,14,17,20,26,29and 32weeks after hatching.Proliferating cell nuclear antigen(PCNA)and Caspase-3immunohistochemisty and light,electron microscopy techniques were used in this study.The results showed that PCNA and Caspase-3positive lymphocytes were distributed in the thymus.The proliferative rates of thymic lymphocytes in the cortex and medulla decreased significantly from 22-26days embryonic stage,and kept stable from 0-3,8-17and 26-32weeks after hatching,but markedly decreased on 5,8,20and 26weeks after hatching.In the same age group,the proliferative rate of lymphocyte in the cortex was higher than that in the medulla.The apoptosis rates of thymic lymphocytes in the cortex and medulla kept unchanged from 22-26days embryonic stage,then increased from 0-8weeks after hatching, and kept stable from 8-17weeks,but rose continually from 20-32weeks.In the same age group, the apoptosis rate of lymphocytes in the cortex was higher than that in the medulla.The nuclei of apoptotic lymphocytes with swollen mitochondria and broken cristae mitochondriales presented different features.The apoptotic bodies were phagocytized by the macrophages.The proliferationand apoptosis of lymphocytes exist universally during the normal embryonic and post embryonic development of the Tianfu duck thymus which undergoes obvious age-related changes,and then supervises and controls the development and regression of this organ cooperatively." @default.
- W2366169401 created "2016-06-24" @default.
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- W2366169401 date "2014-01-01" @default.
- W2366169401 modified "2023-09-24" @default.
- W2366169401 title "Age-related Changes in the Lymphocyte Proliferation and Apoptosis of the Tianfu Duck Thymus" @default.
- W2366169401 hasPublicationYear "2014" @default.
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