Matches in SemOpenAlex for { <https://semopenalex.org/work/W2366196723> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2366196723 abstract "Objective To investigate the expression of insulin-like growth binding protein 5(IGFBP-5),cellular fasassociated death domain-like interleukin-1β-converting enzyme-like inhibitory protein(cFLIP),and high risk-HPV in cervical intraepithelial neoplasia(CIN)and cervical carcinoma(CC)and to evaluate their clinical significances.Methods Immunohistochemistry(SP) was used to determine the expressions of IGFBP-5 and cFLIP proteins in 28 normal cervical tissues,37 CIN and 40 CC tissues,RT-PCR was used to determine the mRNA,and hybrid capture Ⅱ assay was used to determine the high-risk HPV DNA.Results IGFBP-5 protein significantly expressed in normal tissues,CIN and CC tissues,and it was the highest in CINⅡ/Ⅲ but it was decreased in CC tissues(P0.05).IGFBP-5 protein expression had relationships with the clinical stage,cell differentiation and lymph node metastasis.However,IGFBP-5 mRNA expression was higher in the CC group than that in the control group but was lower than that in the CINⅡ/Ⅲ groups.cFLIP expression was not found in normal cervical tissues,but was gradually increased in the CIN and CC groups with an increase of pathological degree(P0.05).Conclusion IGFBP-5,cFLIP and HR-HPV play potential roles in CIN and CC,and could be used to evaluate the progression and prognosis." @default.
- W2366196723 created "2016-06-24" @default.
- W2366196723 creator A5070830488 @default.
- W2366196723 date "2008-01-01" @default.
- W2366196723 modified "2023-09-26" @default.
- W2366196723 title "Expressions of IGFBP-5 and cFLIP in cervical intraepithelial neoplasia and cervical carcinoma and their clinical significances" @default.
- W2366196723 hasPublicationYear "2008" @default.
- W2366196723 type Work @default.
- W2366196723 sameAs 2366196723 @default.
- W2366196723 citedByCount "0" @default.
- W2366196723 crossrefType "journal-article" @default.
- W2366196723 hasAuthorship W2366196723A5070830488 @default.
- W2366196723 hasConcept C104317684 @default.
- W2366196723 hasConcept C105580179 @default.
- W2366196723 hasConcept C121608353 @default.
- W2366196723 hasConcept C126322002 @default.
- W2366196723 hasConcept C143998085 @default.
- W2366196723 hasConcept C190283241 @default.
- W2366196723 hasConcept C204232928 @default.
- W2366196723 hasConcept C207886595 @default.
- W2366196723 hasConcept C2777343196 @default.
- W2366196723 hasConcept C2778220009 @default.
- W2366196723 hasConcept C2993195994 @default.
- W2366196723 hasConcept C502942594 @default.
- W2366196723 hasConcept C55493867 @default.
- W2366196723 hasConcept C71924100 @default.
- W2366196723 hasConcept C86803240 @default.
- W2366196723 hasConceptScore W2366196723C104317684 @default.
- W2366196723 hasConceptScore W2366196723C105580179 @default.
- W2366196723 hasConceptScore W2366196723C121608353 @default.
- W2366196723 hasConceptScore W2366196723C126322002 @default.
- W2366196723 hasConceptScore W2366196723C143998085 @default.
- W2366196723 hasConceptScore W2366196723C190283241 @default.
- W2366196723 hasConceptScore W2366196723C204232928 @default.
- W2366196723 hasConceptScore W2366196723C207886595 @default.
- W2366196723 hasConceptScore W2366196723C2777343196 @default.
- W2366196723 hasConceptScore W2366196723C2778220009 @default.
- W2366196723 hasConceptScore W2366196723C2993195994 @default.
- W2366196723 hasConceptScore W2366196723C502942594 @default.
- W2366196723 hasConceptScore W2366196723C55493867 @default.
- W2366196723 hasConceptScore W2366196723C71924100 @default.
- W2366196723 hasConceptScore W2366196723C86803240 @default.
- W2366196723 hasLocation W23661967231 @default.
- W2366196723 hasOpenAccess W2366196723 @default.
- W2366196723 hasPrimaryLocation W23661967231 @default.
- W2366196723 hasRelatedWork W1539599996 @default.
- W2366196723 hasRelatedWork W1998635752 @default.
- W2366196723 hasRelatedWork W2040785791 @default.
- W2366196723 hasRelatedWork W2166380918 @default.
- W2366196723 hasRelatedWork W2364647120 @default.
- W2366196723 hasRelatedWork W2370129721 @default.
- W2366196723 hasRelatedWork W2371721881 @default.
- W2366196723 hasRelatedWork W2377945850 @default.
- W2366196723 hasRelatedWork W2378071510 @default.
- W2366196723 hasRelatedWork W2383756416 @default.
- W2366196723 hasRelatedWork W2389418545 @default.
- W2366196723 hasRelatedWork W2399096846 @default.
- W2366196723 hasRelatedWork W2435364176 @default.
- W2366196723 hasRelatedWork W2588295625 @default.
- W2366196723 hasRelatedWork W2751424615 @default.
- W2366196723 hasRelatedWork W2995555542 @default.
- W2366196723 hasRelatedWork W2999250672 @default.
- W2366196723 hasRelatedWork W3011335216 @default.
- W2366196723 hasRelatedWork W3148868649 @default.
- W2366196723 hasRelatedWork W3152419125 @default.
- W2366196723 isParatext "false" @default.
- W2366196723 isRetracted "false" @default.
- W2366196723 magId "2366196723" @default.
- W2366196723 workType "article" @default.