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- W2366233074 abstract "【Objective】 The variation of exon 1 and exon 2 of Somatostatin(SST) gene were examined and the association of this polymorphism with growth traits in Qinchuan,Nanyang,Luxi,Luxi×Simmental,Xia'nan and Jiaxian six cattle breeds was investigated.【Method】 Using PCR-SSCP and DNA sequencing technology,669 individuals from six Chinese cattle breeds were selected to check the polymorphism of exon 1,exon 2 of SST gene.Least squares regressions analysis with linear mode was used to analyze the relationship between the genotypes and growth traits.【Result】 Mutations of G126A was detected in the exon 1 of the SST gene.The electrophoretic result showed that there were three genotypes,namely AA,AG and GG in all cattle breeds but for Qinchuan and Luxi×Simmental which had two(GG,AG) genotypes.Allelic frequencies,genotype frequencies and polymorphism information content(PIC) of this SNP were investigated and evaluated by the χ2 test in 669 cattle populations.The result showed that all cattle breeds were in Hardy-Weinberg equilibrium.Allelic frequencies of A,G and polymorphism information content of the bovine SST locus in six breeds varied from 0.053 8 to 0.218 8,0.781 2 to 0.946 2,and 0.096 6 to 0.283 4,respectively.We also obserued a potential association of this SNP with 8 growth traits indexes in 669 individuals and found significant effect on some of the growth indexes.The indexes of animals with the genotype GG were significantly higher than those of AG on bodylength,hip width and hucklebone width in 24-month-old Qinchuan cattle(P0.05);The indexes of animals with the genotype GG were significantly higher than those of AA on bodylength in 12-month-old Luxi cattle(P0.05);While the indexes of animals with the genotype GG were higher than those of AG on bodylength and bodyheight in 12-month-old Luxi×Simmental cattle,the indexes between genotypes were not significant(P0.05).【Conclusion】 We conclude that polymorphisms of the SST gene is potentially associated with cattle growth traits and may be a candidate gene responsible for growth trait in Qinchuan,Luxi and Luxi×Simmental cattle." @default.
- W2366233074 created "2016-06-24" @default.
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- W2366233074 date "2011-01-01" @default.
- W2366233074 modified "2023-09-28" @default.
- W2366233074 title "Polymorphism of SST gene and its association with growth traits in cattle breeds" @default.
- W2366233074 hasPublicationYear "2011" @default.
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