Matches in SemOpenAlex for { <https://semopenalex.org/work/W2366406555> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2366406555 abstract "Objective:To investigate the effect of curcumin on topoismerase I of leukemia K562 cells.Method:FCM and RT-PCR were used to analyze the change of TopoI mRNA and protein.Result:TopoI was highly expressed in K562 cells. Mean fluorescence intensity of TopoI protein in blank group ( 84.31 ± 4.26 ) was significantly higher than that in control group ( 3.82 ± 0.17 , P 0.001 ). Curcumin can significantly inhibit the expression of TopoⅠby FCM and RT-PCR analysis. 25 μmol/L curcumin can inhibit the expression of TopoI. The inhibitory effect of curcumin increased with increasing dosage of curcumin.Conclusion:Curcumin can inhibit the proliferation of K562 cell through inhibiting the expression of TopoI. Curcumin is a new TopoI inhibitor and has a good clinical application prospect." @default.
- W2366406555 created "2016-06-24" @default.
- W2366406555 creator A5058572669 @default.
- W2366406555 date "2006-01-01" @default.
- W2366406555 modified "2023-09-28" @default.
- W2366406555 title "Study on the effect of curcumin on TopoI of K562 cell" @default.
- W2366406555 hasPublicationYear "2006" @default.
- W2366406555 type Work @default.
- W2366406555 sameAs 2366406555 @default.
- W2366406555 citedByCount "0" @default.
- W2366406555 crossrefType "journal-article" @default.
- W2366406555 hasAuthorship W2366406555A5058572669 @default.
- W2366406555 hasConcept C104317684 @default.
- W2366406555 hasConcept C105580179 @default.
- W2366406555 hasConcept C124952713 @default.
- W2366406555 hasConcept C142362112 @default.
- W2366406555 hasConcept C1491633281 @default.
- W2366406555 hasConcept C153911025 @default.
- W2366406555 hasConcept C171122931 @default.
- W2366406555 hasConcept C182141236 @default.
- W2366406555 hasConcept C185592680 @default.
- W2366406555 hasConcept C2778250585 @default.
- W2366406555 hasConcept C55493867 @default.
- W2366406555 hasConcept C86803240 @default.
- W2366406555 hasConcept C98274493 @default.
- W2366406555 hasConceptScore W2366406555C104317684 @default.
- W2366406555 hasConceptScore W2366406555C105580179 @default.
- W2366406555 hasConceptScore W2366406555C124952713 @default.
- W2366406555 hasConceptScore W2366406555C142362112 @default.
- W2366406555 hasConceptScore W2366406555C1491633281 @default.
- W2366406555 hasConceptScore W2366406555C153911025 @default.
- W2366406555 hasConceptScore W2366406555C171122931 @default.
- W2366406555 hasConceptScore W2366406555C182141236 @default.
- W2366406555 hasConceptScore W2366406555C185592680 @default.
- W2366406555 hasConceptScore W2366406555C2778250585 @default.
- W2366406555 hasConceptScore W2366406555C55493867 @default.
- W2366406555 hasConceptScore W2366406555C86803240 @default.
- W2366406555 hasConceptScore W2366406555C98274493 @default.
- W2366406555 hasLocation W23664065551 @default.
- W2366406555 hasOpenAccess W2366406555 @default.
- W2366406555 hasPrimaryLocation W23664065551 @default.
- W2366406555 hasRelatedWork W2102067122 @default.
- W2366406555 hasRelatedWork W2277440300 @default.
- W2366406555 hasRelatedWork W2354089649 @default.
- W2366406555 hasRelatedWork W2354620224 @default.
- W2366406555 hasRelatedWork W2356233572 @default.
- W2366406555 hasRelatedWork W2358167553 @default.
- W2366406555 hasRelatedWork W2360053694 @default.
- W2366406555 hasRelatedWork W2365692732 @default.
- W2366406555 hasRelatedWork W2367364077 @default.
- W2366406555 hasRelatedWork W2372379224 @default.
- W2366406555 hasRelatedWork W2376199469 @default.
- W2366406555 hasRelatedWork W2384186031 @default.
- W2366406555 hasRelatedWork W2384888627 @default.
- W2366406555 hasRelatedWork W2389291413 @default.
- W2366406555 hasRelatedWork W2393691682 @default.
- W2366406555 hasRelatedWork W2569444567 @default.
- W2366406555 hasRelatedWork W2978510651 @default.
- W2366406555 hasRelatedWork W3029238898 @default.
- W2366406555 hasRelatedWork W3030587371 @default.
- W2366406555 hasRelatedWork W3032832874 @default.
- W2366406555 isParatext "false" @default.
- W2366406555 isRetracted "false" @default.
- W2366406555 magId "2366406555" @default.
- W2366406555 workType "article" @default.