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- W2366420527 abstract "Objectives: To study the inhibition of adenosine preconditioning on ischemia-induced systematic inflammatory response to lung injury. Methods: The vivo rabbit ischemia model with occlusion of left pulmonary hilus for 45 minutes was established in this experiment. Sixty white rabbits were divided into three groups, which included group I (n = 20) without ischemia-reperfusion, group Ⅱ(n = 20) with ischemia-reperfusion and Group Ⅲ (n = 20) with adenosine intravenous injection at 10 minutes before ischemia-reperfusion. The changes of left lung wet-dry weight and the expression of CD11b or CD18 were measured in each group at the time of 1, 2 and 4 hours reperfusion after 45 minutes of pulmonary ischemia. Results: In group II, the expression of CD11b or CD18, left lung wet-dry weight were increased significantly after reperfusion (P 0.01). In groupⅢ,the changes were smaller compared with Group II (P 0.05). Conclusion: Adenosine preconditioning can inhibit the expression of CD11b/CD18 on systematic ischemia-induced inflammatory response and prevent ischemia-reperfusion lung endothelium injury." @default.
- W2366420527 created "2016-06-24" @default.
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- W2366420527 date "2005-01-01" @default.
- W2366420527 modified "2023-09-23" @default.
- W2366420527 title "The Effect of Adenosine Preconditioning on the Expression of Neutrophil CD11b/CD18 During Reperfasion Lung Injury in Rabbit" @default.
- W2366420527 hasPublicationYear "2005" @default.
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