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- W2366442783 abstract "Objective To explore the radiological manifestations of viral encephalitides by magnetic resonance imaging(MRI),diffusion weighted imaging(DWI) and 1H magnetic resonance spectroscopy(1H-MRS).Methods The conventional MR imaging,DWI and multivoxel 2D 1H-MRS were performed in 36 cases with acute or subacute viral encephalitis.The data by DWI and 1H-MRS were calculated and analyzed,and statistical analyses were performed by using the software of SAS 8.2.Results Viral encephalitis presented as single(14 cases) or multiple lesions(22 cases),located mainly in cortices,subcortical and periventricular white matter,basal ganglia and thalami.The lesions carried slightly long T1 and long T2 intensity with faint patch shape enhancement on contrast-enhanced image.Abnormalities were found on DWI,including isointensity or slightly hyperintensity in 11 cases,homogeneous hyperintensity in 4 cases,and inhomogeneous hyperintensity in 21 cases.On apparent diffuse coefficient(ADC) map,increased diffusivity of the lesion were demonstrated in 26 cases,and increased and restricted diffusivity were seen in the other 10 cases.The mean ADC value of viral encephalitis was significantly higher than that of normal control tissues [(0.93±0.29)×10-3 and(0.76±0.32)×10-3 mm2/s,P=0.007].On 1H-MRS,choline(Cho),creatin(Cr) and n-acetyl aspartate(NAA) of viral encephalitis were significantly lower than those of normal control tissues [Cho(364.3±56.3) vs(440.2±52.8),P0.01;Cr(178.4±28.2) vs(269.3±37.5),P0.05;NAA(203.7±33.8) vs(386.5±68.5),P0.01].Lactate peak was found in 3 cases.Conclusion DWI and 1H-MRS present the information for the histological and metabolism feature of viral encephalitis,and should be applied as an important supplemental examination besides conventional MRI." @default.
- W2366442783 created "2016-06-24" @default.
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- W2366442783 date "2009-01-01" @default.
- W2366442783 modified "2023-09-24" @default.
- W2366442783 title "MRI,DWI and ~1H-MRS features of viral encephalitis:report of 36 cases" @default.
- W2366442783 hasPublicationYear "2009" @default.
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