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- W2366448400 abstract "Objective:To investigate the abnormal gray matter volume in early Parkinson disease(PD). Methods:15 cases of clinically defined early PD patients and 15 cases of normal controls received scan on 1.5 T MRI system. The T1 WI data were collected. Using voxel-based morphometry(VBM) method to compare the images of brain gray matter between two groups. The results were shown by the statistical parametric mapping. Results:Early PD patients showed decreased gray matter volume in right brain regions involving middle temporal gyrus,inferior temporal gyrus,middle occipital gyrus,fusiform gyrus and increased in left brain regions involving cuneus,lingual gyrus,parahippocampal gyrus,fusiform gyrus,precuneus and precentral gyrus.Conclusion:The VBM method could thoroughly and accurately reflect the abnormal volume of brain gray matter quantitatively which are common in early PD patients,and it also provides the necessary neural imaging evidence for the pathological mechanism of early PD patients." @default.
- W2366448400 created "2016-06-24" @default.
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- W2366448400 date "2015-01-01" @default.
- W2366448400 modified "2023-09-26" @default.
- W2366448400 title "Preliminary MRI study on abnormal gray matter morphology in early Parkinson disease" @default.
- W2366448400 hasPublicationYear "2015" @default.
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