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- W2366455775 abstract "Objective To investigate the antitumor effect of Eupolyphaga fibrinolyric protein on S180 and H22 in vivo.MethodsTumor-bearing mouse model was built in vivo,and the experiments were divided into positive control group(cyclophosphamide),negative control group(saline),the high concentration drug group,the middle concentration drug of group,the low concentration of drug group.The inhibition rate against ascites tumor was calculated by the tumer weights and the rate anainst solid tumor was calculated by the concentration of cells.ResultsEFP had significant inhibition against S180 ascites tumor,when the dose of drug was 2.90 mg/kg,the inhibition rate was 69.56%,higher than that of cyclophosphamide(20 mg/kg)(51.75%).EFP had preferably inhibition against S180 solid tumors,when the dose of drug was 1.45 mg/kg,the inhibition rate was 37.48%,higher than that of cyclophosphamide(20 mg/kg)(35.59%),and a certain dose-dependent.When the drug concentration was 0.73 mg/kg,the H22 solid tumor inhibition rate was 41%,higher than that of cyclophosphamide(20 mg/kg)(37%).ConclusionEFP has obvious antitumor effect on S180 and H22 in vivo." @default.
- W2366455775 created "2016-06-24" @default.
- W2366455775 creator A5066518862 @default.
- W2366455775 date "2010-01-01" @default.
- W2366455775 modified "2023-09-25" @default.
- W2366455775 title "The Antitumour Effect of Eupolyphaga Fibrinolyric Protein on S_(180) and H_(22) in vivo" @default.
- W2366455775 hasPublicationYear "2010" @default.
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