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- W2366481874 abstract "Objective To observe the pathological changes in synovium after sodium hyaluronate treatment of knee osteoarthritis(OA).Methods Sixty patients with OA were randomly divided into two groups,with 30 patients in each group.The observation group was treated with intra-articular injection of sodium hyaluronate.The control group received no treatment.Knee arthroscopy was performed before and after treatment to observe the pathological changes in synovium.Results Before treatment,patients with OA had synovial and capillary hyperplasia and lymphocytic infiltration and fibrosis.After treatment,synovial hyperplasia and lymphocytic infiltration were significantly improved in observation group.Compared with control group,Lequence indexes were obviously decreased by treatment with sodium hyaluronate(P0.05).No abnormalities in liver and kidney function and routine blood indexes were found and no digestive and nervous system lesions and allergy symptoms occurred in observation group.Conclusion Sodium hyaluronate is an effective and safe treatment for improving synovial lesions after knee OA.The effect of knee osteoarthritis synovium after sodium hyaluronate treatment is obvious and the side-effect is few,so they are worth being used." @default.
- W2366481874 created "2016-06-24" @default.
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- W2366481874 date "2013-01-01" @default.
- W2366481874 modified "2023-09-23" @default.
- W2366481874 title "Pathological Changes in Synovium after Sodium Hyaluronate Treatment of Knee Osteoarthritis" @default.
- W2366481874 hasPublicationYear "2013" @default.
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