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- W2366532868 abstract "Acute disseminate d encephalomyelitis(ADEM) is a disease that is characterize d by an immune me diate d inflammatory reaction an d demyelination in the central nervous system, inclu ding optic nerve, brain an d spinal cor d, which is common in chil dren, but also appears in a dults. ADEM happens probably with a causative relationship to viral diseases or prior vaccinations. It can also occur without any cause. The clinical symptoms of ADEM can begin with fever, hea dache an d meningeal signs, followe d by abnormal mental status, seizures an d focal neurological signs, such as limb pareses, visual decline an d speech disturbances. An d their clinical courses may be monophasic, recurrent or multiphasic, mil d but also very aggressive. Neuroimaging may be characterize d by large demyelinating lesions in the brain involving both the white an d the grey matter, an d spinal cor d. Lesions in ADEM are typically large globular lesions,multiple, an d asymmetric, partially with diffuse or ring like ga dolinium enhancement. The diagnosis of ADEM requires both multifocal involvement an d encephalopathy by consensus criteria. The differential diagnoses of ADEM inclu de a variety of disor ders, such as viral encephalitis, multiple sclerosis,neuromyelitis optica spectrum disor ders an d primary central nervous system vasculitis, etc. Treatments of ADEM inclu de corticosteroi ds, intravenous immunoglobulin, plasmapheresis an d other immunosuppressive agents." @default.
- W2366532868 created "2016-06-24" @default.
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- W2366532868 date "2013-01-01" @default.
- W2366532868 modified "2023-09-23" @default.
- W2366532868 title "Acute disseminated encephalomyelitis: a comprehensive review" @default.
- W2366532868 hasPublicationYear "2013" @default.
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