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- W2366603669 abstract "Objective To study the effects of dipsacud asper of the depositioh of amyloid protein in the parietal cortex , and learning and memorizing abilities of Alzheimer's disease(AD) model rats Methods The behaviour test and immunocytochemical method combinating image analysis were adopted Results The behaviour test showed that there were significant differences among three groups during different periods(P0 05 or p0 01) The amyloid protein like immunoreactivity(AP LI) neuron distributed in layer Ⅲ,Ⅳ,Ⅴ of parietal cortex as well as on the wall of blood vessels Image analysis indicated that after AD rats were dealed with the dipsacus asper and Vit E , the average area and optic density (OD) AP LI neuron in the parietal cortex were reduced and decreased respectively There are significant difference between experimental groups and control(P0 05 or P0 01), with the prolongation of medication, these changes become more obvious Conclusions The dipsacus asper has similar effect on AD to Vit E, the mechanisms may be achieved by preventing β AP from depositing and clearing deposited β AP and inhibiting cell excessive oxidation" @default.
- W2366603669 created "2016-06-24" @default.
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- W2366603669 date "2002-01-01" @default.
- W2366603669 modified "2023-09-23" @default.
- W2366603669 title "Effect of dipsacus asper of the deposition of amyloid protein in the parietal cortex of Alzheimer's disease model rats" @default.
- W2366603669 hasPublicationYear "2002" @default.
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