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- W2366637566 abstract "Objective To study the clinical significance of lectinreactive alpha-fetoprotein(AFP-L_3) in early detection of primary hepatocellular carcinoma(PHC).Methods According to the different affinity of lentil lectin with alpha-fetoprotein(AFP),sera from 52 patients with primary PHC and 57 patients with benign liver disease were measured by affinity immunoelectrophoresis blotting to evaluate serum levels of AFP-L_3.Positive criterium is AFP-L_315%.Results The positive rate of AFP-L_3 in the patients with PHC was significantly higher than that in the patients with benign liver disease(P(0.01)).In the cases of AFP≤400 μg/L and AFP400 μg/L,the positive rate of AFP-L_3 was(76.9%) and(84.6%),respectively.The level of AFP-L_3 had no correlation with the level of AFP.The level of AFP had positive correlation with the tumor(r=(0.453),P(0.01)).In the cases of tumors that measured more than 2 cm in diameter,the positive rate of AFPL_3 had no correlation with the the tumor(r=(0.012),P(0.05)).Conclusion Measurement of AFP-L_3 is useful for early detection of PHC in the patients with low level AFP,especially in those with small PHC." @default.
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- W2366637566 date "2007-01-01" @default.
- W2366637566 modified "2023-09-28" @default.
- W2366637566 title "Clinical significance of lectin-reactive alpha-fetoprotein in early detection of primary hepatocellular carcinoma" @default.
- W2366637566 hasPublicationYear "2007" @default.
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