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- W2366751399 abstract "Objective: To observe the preventive effect of chinonin on guinea pig's asthma and explore the partly mechanism. Methods: 67 guinea pigs were divided into five groups at random, the groups of normal, asthma, chinonin, dexamethasone and chinonin + dexamethasone. The ratio of lung weight to body, the period needed for inducing asthma attacking and the sustained period of asthma episode were observed. The NO and ET of serum and bronchia alveolus lavage fluid(BALF) were detected respectively. Results: The inducing and sustained period of asthma episode in chinonin group were significant longer than those in model group, the inflammatory reaction of lung tissue in chinonin group was lightened obviously and the change was similar to the dexamethasone group. The NO in serum and ET-1 of BALF in chinonin group were lower than those in model group, which was similar to the dexamethasone group. Conclusion: Chinonin can partly prevent asthma episode, which was related to the level of NO and ET-1." @default.
- W2366751399 created "2016-06-24" @default.
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- W2366751399 date "2007-01-01" @default.
- W2366751399 modified "2023-09-25" @default.
- W2366751399 title "PREVENTIVE EFFECT OF CHINONIN ON GUINEA PIG'S ASTHMA AND INFLUENCE ON ET AND NO LEVEL" @default.
- W2366751399 hasPublicationYear "2007" @default.
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