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- W2366762197 abstract "The activities of plasma antithrombin Ⅲ(AT-Ⅲ),crude or purified,can be in-hibited by hydroxyl radical produced byCuCl_2/ascorbic acid svstem in vitro,and the purifiedAT-Ⅲ also can be cleavaged by this system,The inhi-bition was dosage-and time-dependent.The higherthe dilution of plasma, the heavier the AT-Ⅲdamagewas observed. The protective effects of 0-0.6mmol·L￣(-1)ethyl gallate, propyl gallate and isobutyl gallateagainst plasma AT-Ⅲ oxidation were dosage-depen-dent. At 0.6mmol·￣(-1),the protection percentageagainst plasma AT-Ⅲ oxidation of these esters wereethyl gallate 48.5%,propyl gallate 39.1%and isobutylgallate 40.0%,respectively. The order of the protectivepotency of these esters and other three anti-thrombotic drugs was pyrazine sodium ferulate catechuicinegallic esters." @default.
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- W2366762197 date "1995-01-01" @default.
- W2366762197 modified "2023-09-25" @default.
- W2366762197 title "Protective effect of gallic esters against hydroxyl radical damage on antithrombin III" @default.
- W2366762197 hasPublicationYear "1995" @default.
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