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- W2366792073 abstract "Objective:To predict the secondary structure and B cell antigenic epitopes of App flic.Method: Based on APP flic amino acid sequence,the secondary structure was predicted by GOR4,PHD and SOPMA;β-turn,accessibility,flexibility,antigenicity and hydrophilicity index were predicted by Chou-Fasman,Emini,Kolaskar and Parker respectively.Result: The results showed that flic was of a non-stable lipoprotein,two casein kinase Ⅱ phosphorylation site and three protein kinase C phosphorylation site were located in No.39-42 SirD,164-167 SvkD and 39-41SiR,161-163TsR,164-166SvK respectively,the most possible B cell epitopes of flic were located in or adjacent to amino acid 55-61 and 152-158.All the predicted epitopes were located in random coil frame of the protein for the secondary structure.Conclusion: These results provided reference and theory basis for research on function of flic and developing genetically engineering vaccine for APP." @default.
- W2366792073 created "2016-06-24" @default.
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- W2366792073 date "2009-01-01" @default.
- W2366792073 modified "2023-09-24" @default.
- W2366792073 title "Prediction of Secondary Structure and B Cell Epitope for flic of Actionobacillus pleuropneumoniae" @default.
- W2366792073 hasPublicationYear "2009" @default.
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