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- W2366884048 abstract "Objective To analyze the metabolic features of polycystic ovary syndrome (PCOS) and especially discuss the characteristics of insulin resistance (IR) in order to provide the clinical basis of treatment and etiology.Methods Clinical datas of 37 patients with PCOS were recruited and analyzed retrospectively. The patients were divided into obese group(n=20) and non-obese group(n=17) in terms of body mass index (BMI).The levels of blood lipid profile, blood pressure and sexual hormones were compared, and the related indexes of IR were discussed in particular.Results (1) The levels of fast blood glucose,blood pressure and levels of sexual hormones had no difference in two groups (all P0.05). (2) Compared with non-obese group, TG and TC were higher (all P0.05), HDL-C was lower (P0.05), while LDL-C had no difference (P0.05) in obese group. (3) Fast insulin, postprandial 2-hour insulin,insulin resistance index were significantly higher (all P0.05), while insulin sensitivity index (ISI) were significantly lower (P0.05) in obese group than those in non-obese group. (4) Area under receiver operating curve of insulin secretion (AUC-I) raised significantly in obese group than that in non-obese group442.55 (292.21~728.09) vs 298.88 (153.81~416.10),P0.05;AUC-I was positively correlated with BMI (r=0.604,P=0.000).Conclusions PCOS has a notable alloplasmic feature. IR is one of the considerable features in PCOS patients, and the degree of IR is significantly higher in obese patients. Obese is an important risk factor for PCOS patients." @default.
- W2366884048 created "2016-06-24" @default.
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- W2366884048 date "2009-01-01" @default.
- W2366884048 modified "2023-09-28" @default.
- W2366884048 title "The metabolic features of polycystic ovary syndrome" @default.
- W2366884048 hasPublicationYear "2009" @default.
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