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- W2366892873 abstract "Objective To investigate the association of serum nesfatin-1 levels with obesity and type 2 diabetes.Methods The serum nesfatin-1 concentrations were measured in 58 type 2 diabetic patients and 30 normal subjects by ELISA.FPG,FIns,HbA1c and lipid profiles were also measured.Results The serum nesfatin-1 concentration was significantly lower in T2DM-OB group than in T2DM-NW group(P 0.05).Significant difference of nesfatin-1 level wasn't found between diabetic patients and normal subjects.We also didn't find significant difference between fasting and postprandial nesfatin-1 levels.Correlation analysis showed that nesfatin-1 was negatively correlated with TG.In a multiple stepwise linear regression analysis,TG was an independent determinant for serum nesfatin-1 concentrations.Conclusions The serum nesfatin-1 concentration is decreased in obese type 2 diabetic patients.Nesfatin-1 may partly contribute to the pathogenesis of insulin resistance in obese diabetic patients." @default.
- W2366892873 created "2016-06-24" @default.
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- W2366892873 date "2012-01-01" @default.
- W2366892873 modified "2023-09-28" @default.
- W2366892873 title "Association of serum nesfatin-1 concentration with obesity and type 2 diabetes" @default.
- W2366892873 hasPublicationYear "2012" @default.
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