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- W2366940703 abstract "OBJECTIVE: To investigate fragmentation pathways of amoxicillin using electrospray ionization multi-stage tandem mass spectrometry,and to provide reference for quality and quantity analysis of amoxicillin.METHODS: Amoxicillin was further purified by high performance liquid chromatography,and the fragmentation mechanisms were investigated by electrospray ionization multi-stage tandem mass spectrometer.RESULTS: The β-lactam ring of amoxicillin has three different opening modes;2 kinds of different m/z:114 ion fragments are obtained by two different fragmentation pathways;m/z:349 ion fragments can be a characteristic fragment of amoxicillin for quality and quantity analysis of amoxicillin.CONCLUSION: The method is sensitive and accurate for further study of transformation and metabolism of amoxicillin and its quality and quantity analysis." @default.
- W2366940703 created "2016-06-24" @default.
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- W2366940703 date "2010-01-01" @default.
- W2366940703 modified "2023-09-23" @default.
- W2366940703 title "Study on Fragmentation Pathways of Amoxicillin by Electrospray Ionization Multi-stage Tandem Mass Spectrometry" @default.
- W2366940703 hasPublicationYear "2010" @default.
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