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- W2366995462 abstract "Objective:To observe the clinical therapeutic effect of a Xianggui Capsule for Syndrome of blood stasis due to cold accumulation of primary dysmenorrhea and its influence on prostaglandin level in menstrual fluid.Methods:180 patients with Syndrome of blood stasis due to cold accumulation of primary dysmenorrhea were assigned equally to the Xianggui Capsule group,the Shaofu Zhuyu Keli group and the control group(oral administrated with compoud aminopyine phenacetin tablets).The treatment course was 3 menstrual cycles.The effect in relieving menalgia was evaluated using numerical rating scale(NRS) before and after treatment and change of PGF2α and PGE2 content in menstrual fluid and uterin artery hemodynamics was tested as well.Results:After treatment,in the Xianggui Capsule group 24 patients(40.00%) were clinically cured,treatment was markedly effective in 16 patients(26.67%),effective in 18(30.00%) and ineffective in 2(3.33%),and in the Shaofu Zhuyu Keli group were 12(20.00%),18(30.00%),26(43.33 %)and 4(6.67%),while the control group were 4(6.67%),24(40.00%),20(33.33%)and 12(20.00%)respectively,the clinical effect in Xianggui Capsule group was superior to that in the control group(P0.05).The NRS score was(0.63±0.67) in the Xianggui Capsule group,Significantly lower than that in the Shaofu Zhuyu Keli group and in the control group,which was(2.56±0.68) and(2.79±0.85) respectively(P0.01).The PGF2α level after treatmentwas significantly lower and the PGE2 level after treatment was significantly higher in the Xianggui Capsule group than that in the Shaofu Zhuyu Keli group and in the control group,respectively(P0.01).There showed no difference in the three aspects between the Shaofu Zhuyu Keli group and the control group(P0.05).Conclusion:Xianggui Capsule has a reliable therapeutic effect on Syndrome of blood stasis due to cold accumulation of primary dysmenorrhea,which is superior to that of Somiton tablet,and its mechanism might be exerted by regulating PGF2αand PGE2 level in menstrual fluid." @default.
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- W2366995462 date "2011-01-01" @default.
- W2366995462 modified "2023-09-24" @default.
- W2366995462 title "Clinical Observation on Treatment of Syndrome of Blood Stasis Due to Cold Accumulation of Primary Dysmenorrhea with Xianggui Capsule" @default.
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