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- W2366996881 abstract "Objective:To investigate the protective effects of compound Nepeta angustifolia on myocardial ischemia/reperfusion-induced injury(I/R) in rats.Method:Sixty SD rats were divided into 6 groups randomly:sham group(onlyneddle not ligation),model group,positive group(compound danshen tablets,1.08 g · kg-1),N.angustifolia groups low-does,medium-does and high-does group(2.9,5.8,11.6 g · kg-1).Rats were continuous gavaged for 7 days,the ligation/relaxat-ion of left anterior descending artery was used to establish acute ischemia/reperfusion model.meanwhile monitoringⅡECG,arrhythmia and infarcted zone.Result:Compared with control,I/R group increased the incidence of reperfusion arrhythmia,infarcted zone and growth of J point and ST-T wave(P0.01).Compared with I/R group,N.angustifolia groups reduced the incidence of reperfusion arrhythmia;delaying arrhythmia time;shorten the arrhythmia duration;diminished infarcted zone;reduced the growth of J point and ST-T wave on ECG,also slowed the heart rate of rats(P0.01,P0.05).Conclusion:N.angustifolia can play a protective role in myocardial ischemia/reperfusion-induced injury,which maybe relate to that N.angustifolia can reduce the incidence of arrhythmia;diminish infarcted zone;reduce the growth of ST-T wave and J point." @default.
- W2366996881 created "2016-06-24" @default.
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- W2366996881 date "2013-01-01" @default.
- W2366996881 modified "2023-09-24" @default.
- W2366996881 title "Protective Effect of Nepeta angustifolia on Myocardial Ischemic/Reperfused Injury in Rats" @default.
- W2366996881 hasPublicationYear "2013" @default.
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