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- W2367001182 abstract "Objective To evaluate cervicovanginal insulin growth factor binding protein-1(IGFBP-1) and cervical sonography in the prediction of preterm labor.Methods Transvaginal sonography was performed in women with threatened preterm labor to measure the length of uterine cervix,width of cervical internal os and cervical index and IGFBP-1 was measured as a predictive indicator.Random and self-control study was conducted.Results ① In the threatened preterm labor group,the cervical length was shorter[(2.56±0.62)cm vs.(3.74±0.71)cm,t=4.659,P0.001]and the cervical index was higher[(0.68±0.21)vs.(0.35±0.23),t=8.762,P0.001)]than normal pregnancy women.The cervical length was significantly shorter [(1.61±0.22)cm vs.(2.69±0.51)cm,t=6.221,P0.001]and the cervical index was higher[(0.85±0.26)vs.(0.63±0.24),t=2.513,P0.05)]in the 9 cases with preterm labor than the other 53 women without preterm labor.② Nine out of 11 women(81.82%) with funnel-shaped cervical internal os in the threatened preterm labor group resulted in preterm labor.All of the normal pregnant women presented T-shaped cervical internal os.③ Twenty-seven out of 63(43.55%) women with threatened preterm labor were IGFBP-1 positive,whose symptoms disappeared after treatment.Nine women with threatened preterm labor and positive IGFBP-1 were admitted in the hospital and turned out preterm labor within 1-3 days.All of the normal pregnant women(78 cases) were IGFBP-1 negative.④ After treatment,the symptoms of threatened preterm labor disappeared in the 27 cases of IGFBP-1 positive and 18(66.67%) became negative in 2 weeks.The cervical length increased after treatment in the threatened preterm labor group at the average growth of 0.56 cm.Conclusions The cervicovanginal IGFBP-1 and the cervical sonography are reliable and objective indicators of preterm labor,which are helpful in predicting the prognosis and follow up after management.The cervical length≤2.5 cm,the cervical index ≥0.5,funnel-shaped cervical internal os and IGFBP-1 positive indicate a high risk of preterm delivery,and intensive management is required." @default.
- W2367001182 created "2016-06-24" @default.
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- W2367001182 date "2008-01-01" @default.
- W2367001182 modified "2023-09-23" @default.
- W2367001182 title "Evaluation of cervicovanginal insulin growth factor binding protein-1 and cervical sonography in the prediction of preterm labor" @default.
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