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- W2367044518 abstract "Purpose: To compare gene expression of P53-TIGAR-HKII to different training program.Method: 30 rats were distributed into three groups: sedentary(C),interval sprint training(F) and endurance training(E).After 6 weeks,gastrocnemius was excised during 24~48h after the last treadmill test and analyzed.Result:1)there was no significant difference on P53 gene expression among E and C and F group.2) TIGARmRNA gene expression was increased in E group.There was no marked difference between F and C group,F and E group on both gene transcription and translation.3) There was no marked difference on HKII gene transcription among E and C and F group.4) There was a highly upregulation in F group versus C group on the content of lactic acid,but no marked difference both in E versus C and E versus F group.Conclusion:1) Endurance training and sprint interval training have no effect on P53 gene expression.2) Endurance training mostly inhibits the glycolysis signal pathway and facilitating aerobic respiration at the same time.3) The stronger control to blood sugar homeostasis of the two training programs will be important to maintain the normal physiological function. 4) Endurance training inhibits the glycolysis signal pathway regulated by P53 in some extent,but similarly sprint interval training have no obviously effect to the glycolysis signal pathway." @default.
- W2367044518 created "2016-06-24" @default.
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- W2367044518 date "2011-01-01" @default.
- W2367044518 modified "2023-09-22" @default.
- W2367044518 title "Effects of Different Exercises on Gene Expression of P53-TIGAR-HKII and the Content of Lactic Acid" @default.
- W2367044518 hasPublicationYear "2011" @default.
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