Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367051977> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2367051977 abstract "Objective To investigate the effects of social isolation and unpredictable during adolescence on adult emotional behaviors in rats.Methods Male SD rats were given 2-week social isolation or unpredictable during adolescence(postnatal day 28~41,PND28~41).After a 3-week recovery,a variety of emotional behaviors were tested in rats during adulthood.Sucrose preference test and forced swim test(FST) were used to evaluate depression-like behaviors,while open field and elevated plus-maze(EPM) were used to evaluate anxiety-like behaviors.Results Adolescent social isolation had no effects on all tested emotional behaviors of adult rats(P0.05).Unpredictable during adolescence had no effect on sucrose preference of adult rats [(0.86±0.19) vs(0.86±0.03),P0.05],while increased immobility behavior [(29.88±3.37) vs(19.90±3.19),P0.05] and decreased climbing behavior [(24.00±1.67) vs(32.90±3.09),P0.05] in FST,which suggested that unpredictable did not affect intrinsic preference for sucrose of adult rats,but impaired behaviors implicated in motivation and coping.Rats exposed to unpredictable developed highly significant despair behaviors after acute severe in adulthood.In addition,adult rats exposed to unpredictable during adolescence showed more closed arm entries [(176.90±17.01) vs(136.48±9.47),P0.05] and less open arm entries [(3.00±0.93) vs(5.90±1.08),P0.05],demonstrating an increased levels of anxious behaviors.Conclusions Social isolation and unpredictable during adolescence have different effects on adult emotional behaviors in rats.Unpredictable can effectively induce profound and long-lasting changes of emotional behaviors.The present study suggests that adolescent unpredictable stress model may serve as an stress-induced animal model of depression." @default.
- W2367051977 created "2016-06-24" @default.
- W2367051977 creator A5081958736 @default.
- W2367051977 date "2011-01-01" @default.
- W2367051977 modified "2023-09-26" @default.
- W2367051977 title "Adolescent social isolation and unpredictable stress have different effects on emotional behaviors in adult rats" @default.
- W2367051977 hasPublicationYear "2011" @default.
- W2367051977 type Work @default.
- W2367051977 sameAs 2367051977 @default.
- W2367051977 citedByCount "0" @default.
- W2367051977 crossrefType "journal-article" @default.
- W2367051977 hasAuthorship W2367051977A5081958736 @default.
- W2367051977 hasConcept C118552586 @default.
- W2367051977 hasConcept C126322002 @default.
- W2367051977 hasConcept C136569192 @default.
- W2367051977 hasConcept C138496976 @default.
- W2367051977 hasConcept C15744967 @default.
- W2367051977 hasConcept C162324750 @default.
- W2367051977 hasConcept C173586616 @default.
- W2367051977 hasConcept C175444787 @default.
- W2367051977 hasConcept C18903297 @default.
- W2367051977 hasConcept C2776035688 @default.
- W2367051977 hasConcept C2776893239 @default.
- W2367051977 hasConcept C2779085643 @default.
- W2367051977 hasConcept C2779177272 @default.
- W2367051977 hasConcept C2779213276 @default.
- W2367051977 hasConcept C2781249084 @default.
- W2367051977 hasConcept C2992926266 @default.
- W2367051977 hasConcept C42407357 @default.
- W2367051977 hasConcept C46312422 @default.
- W2367051977 hasConcept C558461103 @default.
- W2367051977 hasConcept C70410870 @default.
- W2367051977 hasConcept C71924100 @default.
- W2367051977 hasConcept C73282008 @default.
- W2367051977 hasConcept C86803240 @default.
- W2367051977 hasConcept C95038775 @default.
- W2367051977 hasConceptScore W2367051977C118552586 @default.
- W2367051977 hasConceptScore W2367051977C126322002 @default.
- W2367051977 hasConceptScore W2367051977C136569192 @default.
- W2367051977 hasConceptScore W2367051977C138496976 @default.
- W2367051977 hasConceptScore W2367051977C15744967 @default.
- W2367051977 hasConceptScore W2367051977C162324750 @default.
- W2367051977 hasConceptScore W2367051977C173586616 @default.
- W2367051977 hasConceptScore W2367051977C175444787 @default.
- W2367051977 hasConceptScore W2367051977C18903297 @default.
- W2367051977 hasConceptScore W2367051977C2776035688 @default.
- W2367051977 hasConceptScore W2367051977C2776893239 @default.
- W2367051977 hasConceptScore W2367051977C2779085643 @default.
- W2367051977 hasConceptScore W2367051977C2779177272 @default.
- W2367051977 hasConceptScore W2367051977C2779213276 @default.
- W2367051977 hasConceptScore W2367051977C2781249084 @default.
- W2367051977 hasConceptScore W2367051977C2992926266 @default.
- W2367051977 hasConceptScore W2367051977C42407357 @default.
- W2367051977 hasConceptScore W2367051977C46312422 @default.
- W2367051977 hasConceptScore W2367051977C558461103 @default.
- W2367051977 hasConceptScore W2367051977C70410870 @default.
- W2367051977 hasConceptScore W2367051977C71924100 @default.
- W2367051977 hasConceptScore W2367051977C73282008 @default.
- W2367051977 hasConceptScore W2367051977C86803240 @default.
- W2367051977 hasConceptScore W2367051977C95038775 @default.
- W2367051977 hasLocation W23670519771 @default.
- W2367051977 hasOpenAccess W2367051977 @default.
- W2367051977 hasPrimaryLocation W23670519771 @default.
- W2367051977 hasRelatedWork W1497803939 @default.
- W2367051977 hasRelatedWork W1753989155 @default.
- W2367051977 hasRelatedWork W1963531087 @default.
- W2367051977 hasRelatedWork W2021925971 @default.
- W2367051977 hasRelatedWork W2022585706 @default.
- W2367051977 hasRelatedWork W2068968703 @default.
- W2367051977 hasRelatedWork W2167524177 @default.
- W2367051977 hasRelatedWork W2334026052 @default.
- W2367051977 hasRelatedWork W2348078953 @default.
- W2367051977 hasRelatedWork W2357920043 @default.
- W2367051977 hasRelatedWork W2573754931 @default.
- W2367051977 hasRelatedWork W2579544063 @default.
- W2367051977 hasRelatedWork W2579947866 @default.
- W2367051977 hasRelatedWork W2809304242 @default.
- W2367051977 hasRelatedWork W3070576991 @default.
- W2367051977 hasRelatedWork W3082341677 @default.
- W2367051977 hasRelatedWork W3095167763 @default.
- W2367051977 hasRelatedWork W3132816388 @default.
- W2367051977 hasRelatedWork W3158690718 @default.
- W2367051977 hasRelatedWork W2553715659 @default.
- W2367051977 isParatext "false" @default.
- W2367051977 isRetracted "false" @default.
- W2367051977 magId "2367051977" @default.
- W2367051977 workType "article" @default.