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- W2367072015 abstract "Objective To study the effect of glucocorticoid in combination with small dose of rituxan on primary immune thrombocytopenia. Methods One hundred and twenty cases of primary immune thrombocytopenia patients from January 2012 to January 2014 in Jiangmen central hospital were selected as the research object and randomly divided into control group and intervention group with 60 cases in each group. The control group were given high-dose dexamethasone therapy on the basis of conventional treatment,and intervention group received large dose of dexamethasone and small dose of rituxan joint treatment on the basis of conventional treatment. Platelet number were regularly tested,and the clinical effect of corticosteroids in combination with small dose of rituximab on primary immune thrombocytopenia was comprehensively analyzed. Results Compared with control group,the total effective rate of intervention group was 90. 00%,and the difference was statistically significant( P 0. 05). The incidence of adverse reactions between the two groups had no significant difference( P 0. 05). The patients with platelet number 6 weeks basic stability in intervention group accounted for 70. 00%,which was significantly higher than that of the control group( 25. 00%),and the difference was statistically significant( P 0. 05). Conclusion The clinical effect of glucocorticoid in combination with small dose of rituxan on primary immune thrombocytopenia is significant,and is worthy of further popularization and application in clinic." @default.
- W2367072015 created "2016-06-24" @default.
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- W2367072015 date "2015-01-01" @default.
- W2367072015 modified "2023-09-24" @default.
- W2367072015 title "Clinical effect observation of glucocorticoid in combination with small dose of rituxan in treating primary immune thrombocytopenia" @default.
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