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- W2367085987 abstract "Objective To measure the type Ⅱ 5 alpha-reductase activity in boys with isolated hypospadias.Methods From April 2005 to September 2005,the type Ⅱ 5 alpha-reductase activity was measured in foreskin specimens of 22 boys with isolated hypospadias and was compared to that of healthy control subjects.A spectrophotometer was used to measure the changes of the product NADPH by monitoring the variation in absorbance at 340 nm.Results The activity of type Ⅱ 5 alpha-reductase did not show any significant difference between tissues acquired from boys with isolated hypospadias and normal tissues obtained from the control group(0.3014±0.0054) vs.(0.3065±0.0032) μmol/L·min).Compared to the control group,the type Ⅱ 5 alpha-reductase activity was slightly lower in the patient group.Conclusion There is no difference of type Ⅱ 5 alpha-reductase activity in the foreskin specimens between patients with isolated hypospadias and the control group.This method of measuring type Ⅱ 5 alpha-reductase activity has the advantages of being easy to perform." @default.
- W2367085987 created "2016-06-24" @default.
- W2367085987 creator A5074447759 @default.
- W2367085987 date "2008-01-01" @default.
- W2367085987 modified "2023-09-27" @default.
- W2367085987 title "Assessment of typeII5 alpha-reductase activitiy in boys with isolated hypospadias" @default.
- W2367085987 hasPublicationYear "2008" @default.
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