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- W2367200770 abstract "It has been found that the synthesis of melanin in melanophores was suppressed after 850 nm micro-laser irradiation,due to the reduced expression of tyrosinase. Herein,a preliminary study of the in vivo whitening effect of 850 nm micro-laser on C57 BL /6J mice was carried out using Raman spectroscopy and fluorescence spectroscopy. The characteristic peaks of melanin( 1 405 cm-1and 1 609 cm-1) became obvious when the skin tissue was abundant of melanin.The Raman signals of melanin reduced significantly after 850 nm micro-laser irradiation. Melanin also emitted strong fluorescence under NIR excitation,which also reduced after micro-laser irradiation. The relative Raman intensities and fluorescence intensities were then calculated to quantitatively analyze the whitening effect of 850 nm micro-laser. Finally,the availability of spectroscopic detection means was verified by routine histological examinations( HE and FontanaMasson staining). As a result,spectroscopic technology was a simple and effective means for real-time detection of melanin related physiological events." @default.
- W2367200770 created "2016-06-24" @default.
- W2367200770 creator A5068320905 @default.
- W2367200770 date "2015-01-01" @default.
- W2367200770 modified "2023-09-23" @default.
- W2367200770 title "The Whitening Effect of 850 nm Micro-laser∶ A Spectroscopic Study" @default.
- W2367200770 hasPublicationYear "2015" @default.
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