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- W2367239202 abstract "Objective To observe the clinical effect of endemic arsenism with traditional chinese medication and organic selenium,and to explore the effective medication of treatment of endemic arsenism.Methods One hundred and seventy-five endemic arsenism patients were randomly divided four groups according to factorial experiment design.Four groups included the treatment group with organic selenium,the treatment group with Chinese medication,the treatment group with Chinese medication and organic selenium and the control group.The activities of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px) and glutathione S-transferase(GSTs),the levels of malondialdehyde(MDA)and the level of immunoglobulin G(IgG)were determined before and after therapy.Results During 175 patients,the 46 patients was hyperten sion,the detection rate was 26.3%;37 patients was electrocardiogram abnormal,the abnormal rate was 21.1%.The groups were compared in front and behind of treatment:①The four groups were compared by the content medication(without considering selenium),the activity of SOD in treatment group with traditional chinese medication was higher(P0.01),the activity of GSTs and the levels of MDA and IgG were lower(P0.05 or P0.01).② Comparing with the treatment group without selenium(without considering traditional chinese medication),the activity of SOD in treatment group with organic selenium was higher(P0.01),the level of IgG was lower(P0.01).③The activity of SOD was increased by the joint action of selenium and traditional Chinese medication(P0.05).The levels of MDA and IgG were decreased by the selenium(P0.05 or P0.01).The activity of GSTs,the levels of MDA and IgG were decreased by the traditional Chinese medication.Conclusions Selenium and traditional Chinese medication could enhance the antioxidative capability of body and prevent antioxidative damage.Selenium and traditional Chinese medication had the effect on treating for endemic arsenism.Traditional Chinese medication might be researched and developed for the treatment of endemic arsenism to avoid the side effect of organic selenium." @default.
- W2367239202 created "2016-06-24" @default.
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- W2367239202 date "2009-01-01" @default.
- W2367239202 modified "2023-09-23" @default.
- W2367239202 title "Observation of clinical effect of treatment of endemic arsenism with traditional Chinese medication and organic selenium" @default.
- W2367239202 hasPublicationYear "2009" @default.
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