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- W2367264686 abstract "Objective To explore the role of Fractalkine/Cx3CR1 in the formation and progression of psoriasis,and to study the correlation between Fractalkine/Cx3CR1 expression with PASI.Methods The expression of Fractalkine was examined by immunohistochemical analysis in serial sections of psoriasis biopsies obtained from 26 patients,8 samples of the uninvolved skin on the edge 0.5 cm to the lesions,and 15 normal controls.Results Fractalkine were strongly expressed on endothelial cells and keratocytes in skin lesions of patients with psoriasis but not in normal skin,or lesser expression on the univolved skin(P0.05).The expression of Fractalkine in psoriasis lesions was well correlated with PASI(γ=0.6097,P0.01).Conclusion Fractalkine / Cx3CR1 play an initial role in the psoriasis,can be a target for the treatment." @default.
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- W2367264686 date "2007-01-01" @default.
- W2367264686 modified "2023-09-26" @default.
- W2367264686 title "Expression of Fractalkine and Its Rceseptor Cx3CR1 in Skin Lesion of Patients with Psoriasis Vulgaris" @default.
- W2367264686 hasPublicationYear "2007" @default.
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