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- W2367291279 abstract "OBJECTIVE:To evaluate the relationship between polymorphisms of XRCC1(X-ray cross-complementing group 1) at Arg399Gln loci and lung cancer. METHODS: Literatures searched on CBM disk and Medline were enrolled in the Meta-analysis. The Meta-analysis was applied with Rev Man4.2 software for heterogeneity test and calculation of pooled OR value. RESULTS: Fifteen case-control studies with 6 818 cases and 7 610 controls were analysed by the fixed-effect meta-analysis method. The pooled OR values of Arg/Gln and Gln/Gln compared to Arg/Arg were 0.99 (95% CI: 0.91-1.06) and 1.04 (95% CI: 0.92-1.17), Z statistics were -0.37 and 0.67, and their responding P values were 0.71 and 0.50. CONCLUSION: Although bias cannot be excluded, the findings suggeste that genetic polymorphism of XRCC1 DNA repair gene at Arg399Gln loci might not contribute to the susceptibility of lung cancer." @default.
- W2367291279 created "2016-06-24" @default.
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- W2367291279 date "2006-01-01" @default.
- W2367291279 modified "2023-09-26" @default.
- W2367291279 title "DNA repair gene XRCC1 at Arg399Gln loci polymorphism and lung cancer susceptibility: a Meta-analysis" @default.
- W2367291279 hasPublicationYear "2006" @default.
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