Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367312691> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2367312691 abstract "Objective To investigate the pharmacokinetic parameters of tetrandrine following subconjunctival administration.Methods Sixteen rabbits were given subconjunctival administration by a single dose of tetrandrine 5 mg,the concentrations of tetrandrine in aqueous humor at various time were determined by HPLC,and the pharmacokinetic parameters were analyzed by DSA.Results The concentration-time data of tetrandrinein aqueous humor was subject to two-compartment open model.The pharmacokinetic parameters were as follows:t1/2α 0.533 h,t1/2β 0.69 h,AUC(0-∞)17.762 mg·h·L-1,K10 4.087 h-1,K12 2.787 h-1,K21 1.005 h-1,t1/2Ka 0.398 h.Conclusions Tetrandrine can penetrate blood-aqueous barrier to enter aqueous humor,its distribution and clearance are fast." @default.
- W2367312691 created "2016-06-24" @default.
- W2367312691 creator A5080143961 @default.
- W2367312691 date "2009-01-01" @default.
- W2367312691 modified "2023-09-23" @default.
- W2367312691 title "Pharmacokinetics of tetrandrine in aqueous humor of rabbit following subconjunctival administration" @default.
- W2367312691 hasPublicationYear "2009" @default.
- W2367312691 type Work @default.
- W2367312691 sameAs 2367312691 @default.
- W2367312691 citedByCount "0" @default.
- W2367312691 crossrefType "journal-article" @default.
- W2367312691 hasAuthorship W2367312691A5080143961 @default.
- W2367312691 hasConcept C110121322 @default.
- W2367312691 hasConcept C112705442 @default.
- W2367312691 hasConcept C118487528 @default.
- W2367312691 hasConcept C134306372 @default.
- W2367312691 hasConcept C147789679 @default.
- W2367312691 hasConcept C179998833 @default.
- W2367312691 hasConcept C184651966 @default.
- W2367312691 hasConcept C185592680 @default.
- W2367312691 hasConcept C2779934757 @default.
- W2367312691 hasConcept C2993390227 @default.
- W2367312691 hasConcept C33923547 @default.
- W2367312691 hasConcept C43617362 @default.
- W2367312691 hasConcept C71924100 @default.
- W2367312691 hasConcept C98274493 @default.
- W2367312691 hasConceptScore W2367312691C110121322 @default.
- W2367312691 hasConceptScore W2367312691C112705442 @default.
- W2367312691 hasConceptScore W2367312691C118487528 @default.
- W2367312691 hasConceptScore W2367312691C134306372 @default.
- W2367312691 hasConceptScore W2367312691C147789679 @default.
- W2367312691 hasConceptScore W2367312691C179998833 @default.
- W2367312691 hasConceptScore W2367312691C184651966 @default.
- W2367312691 hasConceptScore W2367312691C185592680 @default.
- W2367312691 hasConceptScore W2367312691C2779934757 @default.
- W2367312691 hasConceptScore W2367312691C2993390227 @default.
- W2367312691 hasConceptScore W2367312691C33923547 @default.
- W2367312691 hasConceptScore W2367312691C43617362 @default.
- W2367312691 hasConceptScore W2367312691C71924100 @default.
- W2367312691 hasConceptScore W2367312691C98274493 @default.
- W2367312691 hasLocation W23673126911 @default.
- W2367312691 hasOpenAccess W2367312691 @default.
- W2367312691 hasPrimaryLocation W23673126911 @default.
- W2367312691 hasRelatedWork W139530009 @default.
- W2367312691 hasRelatedWork W2023708189 @default.
- W2367312691 hasRelatedWork W2076397231 @default.
- W2367312691 hasRelatedWork W2356974456 @default.
- W2367312691 hasRelatedWork W2357332590 @default.
- W2367312691 hasRelatedWork W2357871852 @default.
- W2367312691 hasRelatedWork W2363317946 @default.
- W2367312691 hasRelatedWork W2363996733 @default.
- W2367312691 hasRelatedWork W2366482243 @default.
- W2367312691 hasRelatedWork W2368966635 @default.
- W2367312691 hasRelatedWork W2370851379 @default.
- W2367312691 hasRelatedWork W2373180526 @default.
- W2367312691 hasRelatedWork W2374197944 @default.
- W2367312691 hasRelatedWork W2376932898 @default.
- W2367312691 hasRelatedWork W2378971862 @default.
- W2367312691 hasRelatedWork W2390849530 @default.
- W2367312691 hasRelatedWork W2393066315 @default.
- W2367312691 hasRelatedWork W2410991440 @default.
- W2367312691 hasRelatedWork W2419223191 @default.
- W2367312691 hasRelatedWork W3029701581 @default.
- W2367312691 isParatext "false" @default.
- W2367312691 isRetracted "false" @default.
- W2367312691 magId "2367312691" @default.
- W2367312691 workType "article" @default.