Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367335916> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2367335916 abstract "ObjectiveTo investigate the effects of the monoclonal natural antibody 3B4 on germ tube formation of Candida albicans,and to analyze the features of antigens on C.albicans recognized by 3B4.MethodsC.albicans were inoculated with antibody 3B4,and the ratio of C.albicans with germ tubes growing out was counted.Indirect immunofluorescence and fluoresce cytometry were used to analyze the binding sites of C.albicans by 3B4.Proteinase K digestion and mild alkaline oxidation were used to analyze the antigens recognized by 3B4.ResultsComparing to the isotype control,3B4 could effectively inhibit the germ tube formation of C.albicans.Indirect immunofluorescence and fluoresce cytometry showed that 3B4 mainly binded to the germ tubes.And after treatment by proteinase K or alkaline oxidation,3B4 could no longer identified the germ tube or yeast of C.albicans,indicating that the biochemical features of the antigen recognized by 3B4 were glycoproteins.Conclusionnatural monoclonal antibody 3B4 can bind to a glycoprotein on the germ tube of C.albicans and inhibit its germination,which makes a foundation for further research on the mechanism of 3B4’s inhibitory effect on germination." @default.
- W2367335916 created "2016-06-24" @default.
- W2367335916 creator A5046004370 @default.
- W2367335916 date "2007-01-01" @default.
- W2367335916 modified "2023-09-24" @default.
- W2367335916 title "Preliminary Study on the Mechanism of Monoclonal Natural Antibody 3B4 on Inhibiting the Germination of Candida Albicans" @default.
- W2367335916 hasPublicationYear "2007" @default.
- W2367335916 type Work @default.
- W2367335916 sameAs 2367335916 @default.
- W2367335916 citedByCount "0" @default.
- W2367335916 crossrefType "journal-article" @default.
- W2367335916 hasAuthorship W2367335916A5046004370 @default.
- W2367335916 hasConcept C145081991 @default.
- W2367335916 hasConcept C147483822 @default.
- W2367335916 hasConcept C153911025 @default.
- W2367335916 hasConcept C159654299 @default.
- W2367335916 hasConcept C203014093 @default.
- W2367335916 hasConcept C2778236600 @default.
- W2367335916 hasConcept C2780917455 @default.
- W2367335916 hasConcept C36755584 @default.
- W2367335916 hasConcept C542903549 @default.
- W2367335916 hasConcept C86803240 @default.
- W2367335916 hasConcept C89423630 @default.
- W2367335916 hasConceptScore W2367335916C145081991 @default.
- W2367335916 hasConceptScore W2367335916C147483822 @default.
- W2367335916 hasConceptScore W2367335916C153911025 @default.
- W2367335916 hasConceptScore W2367335916C159654299 @default.
- W2367335916 hasConceptScore W2367335916C203014093 @default.
- W2367335916 hasConceptScore W2367335916C2778236600 @default.
- W2367335916 hasConceptScore W2367335916C2780917455 @default.
- W2367335916 hasConceptScore W2367335916C36755584 @default.
- W2367335916 hasConceptScore W2367335916C542903549 @default.
- W2367335916 hasConceptScore W2367335916C86803240 @default.
- W2367335916 hasConceptScore W2367335916C89423630 @default.
- W2367335916 hasLocation W23673359161 @default.
- W2367335916 hasOpenAccess W2367335916 @default.
- W2367335916 hasPrimaryLocation W23673359161 @default.
- W2367335916 hasRelatedWork W1919706581 @default.
- W2367335916 hasRelatedWork W1926758670 @default.
- W2367335916 hasRelatedWork W2007323771 @default.
- W2367335916 hasRelatedWork W2051970014 @default.
- W2367335916 hasRelatedWork W2096913907 @default.
- W2367335916 hasRelatedWork W2116871349 @default.
- W2367335916 hasRelatedWork W2121293410 @default.
- W2367335916 hasRelatedWork W2289458317 @default.
- W2367335916 hasRelatedWork W2351850831 @default.
- W2367335916 hasRelatedWork W2370812427 @default.
- W2367335916 hasRelatedWork W2371358652 @default.
- W2367335916 hasRelatedWork W2374772540 @default.
- W2367335916 hasRelatedWork W2374788590 @default.
- W2367335916 hasRelatedWork W2513743866 @default.
- W2367335916 hasRelatedWork W2912396408 @default.
- W2367335916 hasRelatedWork W2923869583 @default.
- W2367335916 hasRelatedWork W2954051399 @default.
- W2367335916 hasRelatedWork W3034100904 @default.
- W2367335916 hasRelatedWork W2491176691 @default.
- W2367335916 hasRelatedWork W3031781595 @default.
- W2367335916 isParatext "false" @default.
- W2367335916 isRetracted "false" @default.
- W2367335916 magId "2367335916" @default.
- W2367335916 workType "article" @default.