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- W2367345573 abstract "Objective:To assess the value of domestic qualitative reagents for anti-HBs in evaluating immunity to hepatitis B virus(HBV).Methods:A total of 1016 sera with negative HBsAg were tested for anti-HBs with domestic qualitative ELISA and Abbott quantitative reagents.The agreement and differences of the results with various reagents were statistically analyzed.Results:Of the 1016 sera,639 cases(62.9%) and 742 cases(73.0%) were positive for anti-HBs detected by the domestic reagents and Abbott quantitative reagents respectively(χ2 = 23.98,P 0.001).By detection with the domestic reagents,four hundred and forty(99.1%) of 444 sera with anti-HBs ≥100 mIU/ml and 77(92.8%) of 83 sera with anti-HBs 50-99 mIU/ml were also positive.However,domestic qualitative reagents showed positive only in 112(52.1%) of 215 sera with anti-HBs 10-49 mIU/ml.On the other hand,269(98.2%) of 274 sera with anti-HBs 10 mIU/ml were also negative detected with the domestic reagents.Conclusion:The domestic qualitative reagents for anti-HBs show high specificity and high agreement with Abbott quantitative reagents in detecting sera with anti-HBs ≥50 mIU/ml,although the formers have low sensitivity in testing sera with anti-HBs 50 mIU/ml.The positive rate of anti-HBs defined by domestic qualitative reagents indicates the immunity to hepatitis B virus without further quantitative measurement." @default.
- W2367345573 created "2016-06-24" @default.
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- W2367345573 date "2013-01-01" @default.
- W2367345573 modified "2023-09-28" @default.
- W2367345573 title "Evaluation of domestic qualitative reagents for detecting anti-HBs in assessing the immunity to hepatitis B virus" @default.
- W2367345573 hasPublicationYear "2013" @default.
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