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- W2367365001 abstract "Objectives To investigate the relationship between T cell subsets and the different subtype of Henoch-Schonlein purpura (HSP),explore the role of T cell subsets in HSP. And further clarify the hypothesis of pathogenesis in different subtype of HSP by assessing the levels of T cell subsets,the complement system,immune complexes and immuno-globulin in patients with HSP. Methods The levels of T cell subsets (CD3?CD4?CD8?CD4/CD8 ) in peripheral blood were determined with flow cytometer in 32 children with HSP in the initial stage without administration of steroid or immune inhibitors. The levels of the complement system(C3?C4?CH50),immune complexes and immuno-globulin(IgG?IgA?IgM?IgE)were also detected. Results The levels of CD3?CD4?and the ratio of CD4/CD8 in children with HSP were significantly lower than that of the controls( P 0.05),while the difference among subtypes of HSP was not significant. Conclusions The disorder of T cell subsets might be associated with childhood HSP." @default.
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- W2367365001 date "2006-01-01" @default.
- W2367365001 modified "2023-09-26" @default.
- W2367365001 title "Study on the T cell subsets in children with Henoch-Schonlein purpura" @default.
- W2367365001 hasPublicationYear "2006" @default.
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