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- W2367406373 abstract "Objective To explore the significance of hyperhomocysteinemia in type 2 diabetes mellitus (DM) with coronary heart disease(CHD) in northern China.Methods Selected 92 patients with type 2 DM and CHD,67 patients with type 2 DM,80 patients with CHD,and 95 healthy controls in Han nationality in northern China.Plasma Hcy levels were measured by fluorescence polarization immunoassay (FPIA)and the plasma folate and vitamin B12 levels by microparticle enzyme immunoassay(MEIA).Results The plasma Hcy levels in DM with CHD group(15.1 μmol/L)were significantly higher than in control group(11.7 μmol/L)and DM group(10.9 μmol/L),but lower than in CHD group(16.6 μmol/L),(P0.05).The levels of plasma folate and vitamin B12 in DM with CHD group were significantly lower than in control group and DM group,but higher than in CHD group(P0.05).Logistic-regression analysis indicated that hyperhomocysteinemia,age and TC were the independent risk factors for CHD.Conclusion Hyperhomocysteinemia was the independent risk factors for DM with CHD in northern Chinese Han population.Hcy may be involved in the pathogenesis and development of CHD in type 2 DM." @default.
- W2367406373 created "2016-06-24" @default.
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- W2367406373 date "2007-01-01" @default.
- W2367406373 modified "2023-09-26" @default.
- W2367406373 title "Hyperhomocysteinemia in Type 2 Diabetes Mellitus with Coronary Heart Disease in Northern Chinese Han Population" @default.
- W2367406373 hasPublicationYear "2007" @default.
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