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- W2367443310 abstract "[Objective] The aim was to discuss the protection of epigallocatechin-3-gallate(EGCG) on human liver cells(L02) from injury.[Method] Through determining cell survival rate,the contents of transaminases(ALT and AST),lactate dehydrogenase(LDH) and MDA and the activity of SOD in the cell culture supernatant,the protection of EGCG on L02 from injury was researched.[Result] Compared with the controlled group,in the model group with liver cell injury,the activity of SOD was decreased significantly,the content of MDA was increased extremely significantly,all the dose groups of EGCG could significantly decrease the content of MDA and the contents of ALT and LDH were increased significantly in its culture supernatant.Compared with the model group,the contents of ALT were decreased significantly in the cell culture supernatants of the dose groups 1.25×10-5,2.50×10-5,5.00×10-5 and 1.00×10-4 mol/L of EGCG and the contents of LDH were decreased significantly in the cell culture supernatants of the dose groups 2.50×10-5,5.00×10-5 and 1.00×10-4 mol/L of EGCG;the dose groups 1.25×10-5 and 2.50×10-5 mol/L of EGCG could extremely significantly increase the activity of SOD and the dose groups 5.00×10-5 and 1.00×10-4 mol/L of EGCG could extremely significantly decrease the content of MDA.[Conclusion] EGCG could reduce the oxidative injury of liver cells caused by CCl4 and H2O2.It had protective effect on liver cells in a dose-dependent manner." @default.
- W2367443310 created "2016-06-24" @default.
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- W2367443310 date "2009-01-01" @default.
- W2367443310 modified "2023-09-28" @default.
- W2367443310 title "Protection of Epigallocatechin-3-gallate on Human Liver Cells from Oxidative Injury" @default.
- W2367443310 hasPublicationYear "2009" @default.
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