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- W2367486524 abstract "Objective To investigate the safety and theoretical basis of percutaneous vetebroplasty (PVP) by observing the effect of PVP in experimental osteoporotic goats.Materials and Methods Fifteen vertebral bodies (study group), selected from L 1～L 5 in 5 osteoporotic goats, were used for PVP and the other 5 vertebral bodies were used as control group. Pedicle of vertebral arch was dissected. Under direct vision, the needle was punctured into the vertebral body, than, polymethylmethacrylate (PMMA), the bone cement, was injected into the body. The temperature at the center, anterior border and posterior border of the vertebral body were separately measured. CT scanning was carried out to check the filling condition of PMMA. The goats were sacrificed three days after the surgery. Five injected vertebrae were selected from the five goats (one from each) for pathologic exam. The remaining 10 injected and 5 controlled vertebrae were isolated, the intervertebral discs and appendages were removed. Using double blind method, the maximum longitudinal load, ultimate strength and modulus of elasticity were estimated.Results The maximum longitudinal load, ultimate strength and modulus of elasticity in the study group after the injection of PMMA were significantly higher than that in the control group (P0.05). The average temperature at the center, anterior border and posterior border of the vertebral body was 51.12℃, 37.31℃ and 37.61℃, respectively. The macro- and micro-pathologic exam showed that the PMMA was diffusely and unevenly distributed between bone trabeculae, being in agreement with CT findings. Conclusion Using proper powder/liquid ratio and injecting PMMA at proper moment are the key point for PVP. Injection of PMMA into the vertebral body can significantly increase the maximum longitudinal load, ultimate strength and modulus of elasticity of the vertebral body." @default.
- W2367486524 created "2016-06-24" @default.
- W2367486524 creator A5065739143 @default.
- W2367486524 date "2003-01-01" @default.
- W2367486524 modified "2023-09-27" @default.
- W2367486524 title "Percutaneous Vertebroplasty: An Experimental Study in Osteoporotic Goats" @default.
- W2367486524 hasPublicationYear "2003" @default.
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