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- W2367496674 abstract "Objective Experiment in vivo has indicated that basic fibroblast growth factor (bFGF) has strong effect on retinal pigment epithelium(RPE) cell. The experiment was to observe the ability of bFGF to accelerate regeneration of RPE in vivo.MethodsGreen argon laser was used to produce lesions in the posterior fundus of pigment rabbits. After irradiation, the eyes were intravitreally injected 3 000U/50μL bFGF. Lesions were evaluated by fundus fluorescein angiography (FFA). Transmitted fluorescein and the fluorescein leakage area were measured by image analysis system.ResultsOn day 1 and day 2 after irradiation, transmitted fluorescein and the fluorescein leakage area of two groups were not significantly different (P=0.534, 0.283,respectively). On day 3 and day 4, the difference was significantly (P=0.018 and 0.007,respectively).ConclusionHuman reconbinant bFGF can accelerate rabbit RPE cell regeneration in vivo and bFGF has no species specificity." @default.
- W2367496674 created "2016-06-24" @default.
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- W2367496674 date "2003-01-01" @default.
- W2367496674 modified "2023-09-24" @default.
- W2367496674 title "Effects of bFGF on regeneration of retinal pigment epithelium cell in vivo" @default.
- W2367496674 hasPublicationYear "2003" @default.
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