Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367509410> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2367509410 abstract "AIM: To investigate the effects of irbesartan on malondialdehyde and superoxide dismuase in diabetic rats. METHODS: Forty male Wistar rats were randomly divided into four groups: control group, diabetic group, irbesartan group and captopril group. At the end of 12 wk, the rats were killed. Urine volume, body weight, kidney weight/body weight, plasma glucose, glycosylated hemoglobin A (HbAlc), urinary β_2-microglobulin(β_2-MG), urinary albumin excretion rate(UAR), creatinine clearance(Ccr), levels of malondialdehyde(MDA) and activity of superoxide dismutase(SOD) in plasma and renal tissues were measured. RESULTS: At the end of 12 wk, urine volume, kidney weight/body weight, plasma glucose, HbAlc, UAR, Ccr, urinary β_2-MG excretion, MDA levels of blood and renal tissue in diabetic rats were significantly higher than those of the control group, while the body weights were much lower than those of the control group (P0.05). UAR, Ccr, urinary β_2-MG and MDA of serum and renal tissue in rats of irbesartan and captopril groups were significantly less than those of diabetic group(P0.05). SOD activity of serum and renal tissue in rats of irbesartan and captopril groups were significantly higher than those of diabetic group(P0.05). CONCLUSION: Irbesartan can delay the progress of renal function injury in diabetic rats. And the mechanism may be that irbesartan can reduce the MDA levels and improve SOD activity in diabetic rats." @default.
- W2367509410 created "2016-06-24" @default.
- W2367509410 creator A5009848606 @default.
- W2367509410 date "2004-01-01" @default.
- W2367509410 modified "2023-09-24" @default.
- W2367509410 title "Effects of irbesartan on malondialdehyde and superoxide dismutase in diabetic rats" @default.
- W2367509410 hasPublicationYear "2004" @default.
- W2367509410 type Work @default.
- W2367509410 sameAs 2367509410 @default.
- W2367509410 citedByCount "0" @default.
- W2367509410 crossrefType "journal-article" @default.
- W2367509410 hasAuthorship W2367509410A5009848606 @default.
- W2367509410 hasConcept C10146269 @default.
- W2367509410 hasConcept C126322002 @default.
- W2367509410 hasConcept C134018914 @default.
- W2367509410 hasConcept C159641895 @default.
- W2367509410 hasConcept C185592680 @default.
- W2367509410 hasConcept C2775838275 @default.
- W2367509410 hasConcept C2776151105 @default.
- W2367509410 hasConcept C2777180221 @default.
- W2367509410 hasConcept C2778401633 @default.
- W2367509410 hasConcept C2779479957 @default.
- W2367509410 hasConcept C2779922275 @default.
- W2367509410 hasConcept C2780091579 @default.
- W2367509410 hasConcept C2780259554 @default.
- W2367509410 hasConcept C2780306776 @default.
- W2367509410 hasConcept C555293320 @default.
- W2367509410 hasConcept C71924100 @default.
- W2367509410 hasConcept C77411442 @default.
- W2367509410 hasConcept C84393581 @default.
- W2367509410 hasConceptScore W2367509410C10146269 @default.
- W2367509410 hasConceptScore W2367509410C126322002 @default.
- W2367509410 hasConceptScore W2367509410C134018914 @default.
- W2367509410 hasConceptScore W2367509410C159641895 @default.
- W2367509410 hasConceptScore W2367509410C185592680 @default.
- W2367509410 hasConceptScore W2367509410C2775838275 @default.
- W2367509410 hasConceptScore W2367509410C2776151105 @default.
- W2367509410 hasConceptScore W2367509410C2777180221 @default.
- W2367509410 hasConceptScore W2367509410C2778401633 @default.
- W2367509410 hasConceptScore W2367509410C2779479957 @default.
- W2367509410 hasConceptScore W2367509410C2779922275 @default.
- W2367509410 hasConceptScore W2367509410C2780091579 @default.
- W2367509410 hasConceptScore W2367509410C2780259554 @default.
- W2367509410 hasConceptScore W2367509410C2780306776 @default.
- W2367509410 hasConceptScore W2367509410C555293320 @default.
- W2367509410 hasConceptScore W2367509410C71924100 @default.
- W2367509410 hasConceptScore W2367509410C77411442 @default.
- W2367509410 hasConceptScore W2367509410C84393581 @default.
- W2367509410 hasLocation W23675094101 @default.
- W2367509410 hasOpenAccess W2367509410 @default.
- W2367509410 hasPrimaryLocation W23675094101 @default.
- W2367509410 hasRelatedWork W1972450434 @default.
- W2367509410 hasRelatedWork W1990492502 @default.
- W2367509410 hasRelatedWork W2128601172 @default.
- W2367509410 hasRelatedWork W2140463384 @default.
- W2367509410 hasRelatedWork W2349206683 @default.
- W2367509410 hasRelatedWork W2350433545 @default.
- W2367509410 hasRelatedWork W2353897335 @default.
- W2367509410 hasRelatedWork W2355116357 @default.
- W2367509410 hasRelatedWork W2356719836 @default.
- W2367509410 hasRelatedWork W2362361104 @default.
- W2367509410 hasRelatedWork W2363283463 @default.
- W2367509410 hasRelatedWork W2366301911 @default.
- W2367509410 hasRelatedWork W2369772234 @default.
- W2367509410 hasRelatedWork W2374956640 @default.
- W2367509410 hasRelatedWork W2379267131 @default.
- W2367509410 hasRelatedWork W2381847529 @default.
- W2367509410 hasRelatedWork W2387722714 @default.
- W2367509410 hasRelatedWork W2389270085 @default.
- W2367509410 hasRelatedWork W2439159290 @default.
- W2367509410 hasRelatedWork W3030320769 @default.
- W2367509410 isParatext "false" @default.
- W2367509410 isRetracted "false" @default.
- W2367509410 magId "2367509410" @default.
- W2367509410 workType "article" @default.