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- W2367513822 abstract "Objective:To find protective antigen(PA) defective mutants of anthrax toxin with the same function as PA but with low immunogenicity,different domains of PA were mutated.Methods:When expressing the defective mutants of PA,it was observed that different mutants had different expression levels by accident.It was also observed that the mutant named PAm4 was expressed solubly and the others were mainly expressed as inclusion body.The characters of the four domains of PA were analyzed by DNAStar software.Results:It showed that the surface probability plot of domain 2 was different from the other domains.Conclusion:The surface probability plot might be the most important factor that affected the solubility of PA mutants." @default.
- W2367513822 created "2016-06-24" @default.
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- W2367513822 date "2008-01-01" @default.
- W2367513822 modified "2023-09-23" @default.
- W2367513822 title "The Effect of Different Domains of Protective Antigen of Anthrax Toxin on its Expression Solubility" @default.
- W2367513822 hasPublicationYear "2008" @default.
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