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- W2367524116 abstract "Objective To discuss the relationship between the sex hormone level and coronary artery stenosis degree of male patients with coronary heart disease(CHD).Methods According to the results of coronary artery angiography,135 male patients were divided into CHD group and control group,and CHD group were subdivided into single branch group,double branch group and multiple branch group,and the stenosis degree of coronary artery was figured by stenosis branch number and Gensini score.The serum concentrations of five sex hormones were detected in all the subjects with radioimmunoassay,including stradiol(E2),testosterone(T),progestone(P),dehydro-epiandrosterone(DHEA) and dehydroepiandrosterone sulfare(DHEAS).The sex hormone levels between different groups were compared and the relationship between sex hormones and coronary artery stenosis level were analyzed.Results The values of T,DHEA and DHEAS were significantly lower in CHD group than those in control group,T(18.6±8.6) nmol/L vs(29.7±11.5) μmol/L,DHEA(22.9±15.3) nmol/L vs(57.9±27.1) nmol/L,DHEAS(5.5±1.3) μmol/L vs(6.4±2.4) μmol/L(P0.05).E2,P and E2/T showed no statistic significance between the two groups or different branch lesions.With the increasing of stenosis branch number,the values of T and DHEA increased(P0.05 or 0.01).DHEA and DHEAS were enrolled into the multiple regression equation,the standard regression coefficients were-0.229 and-0.230.Conclusion The levels of androgens are lower in male patients with CHD.The levels of androgens in men are likely to influence the stenosis degree of coronary artery." @default.
- W2367524116 created "2016-06-24" @default.
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- W2367524116 date "2010-01-01" @default.
- W2367524116 modified "2023-09-23" @default.
- W2367524116 title "Relationship between sex hormone level and coronary artery stenosis degree of male patients with coronary heart disease" @default.
- W2367524116 hasPublicationYear "2010" @default.
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