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- W2367557801 abstract "Objective To isolate fungi from the Yellow River Delta plants,to screen antibiotic fungal strains,and to identify the active microbial products.Methods The isolation of fungi was performed by sucrose density gradient,the antitumor activities and antibacterial activities of the microbial products were assayed by MTT and 2-fold dilution method,respectively,and the active compounds were purified and identified by column chromatography over silica gel and Sephadex LH-20,and analysis of NMR and ESI-MS,respectively.Results 136 fungal strains were isolated from Yellow River Delta plants,25 of them showed antimicrobial activities against Candida albicans and Staphylococcus aureus,and 17 of them showed cytotoxic activities against MCF-7cells.Citrinin was identified from the fermentation broth of Cladosporiumsp.OUCMDZ-2046.And citrinin showed the growth inhibitions of C.albicans and MCF-7breast cancer cells.Conclusion Plant fungi from Yellow River Delta are potential resources for drug discovery and are worthy of being further studied." @default.
- W2367557801 created "2016-06-24" @default.
- W2367557801 creator A5084496183 @default.
- W2367557801 date "2014-01-01" @default.
- W2367557801 modified "2023-09-24" @default.
- W2367557801 title "Isolation and antibiotic screening of fungi associated with plants from Yellow River Delta and identification of the active metabolites" @default.
- W2367557801 hasPublicationYear "2014" @default.
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