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- W2367560769 abstract "Objective: To observe the effect of electroacupuncture (EA) and salvia miltiorrhiza (丹参)on heat-shock protein(Hsp70) mRNA expression in ischemia/reperfusion myocardium and the content of dopamine in blood, and investigate the effect between EA and salvia miltiorrhiza. Methods: Twentyfour rabbits were randomly divided into four groups: control group, EA group, salvia miltiorrhiza group, EA+salvia miltiorrhiza group(n=6 in each group). The ischemia/reperfusion model was established by clipping descending branch of coronary artery for 30 minutes then loosing it for 2 hours. EA and salvia miltiorrhiza were accepted in different groups. The blood content of dopamine was detected before ischemia, 30 minutes ischemic and 2 hours reperfusion. Ischemic and nonischemic myocardium tissues were sampled to observe the expressions of Hsp70 mRNA by reverse transcriptionpolymerase chain reaction(RTPCR) method. The influence of EA and salvia miltiorrhiza on the expression of Hsp70 mRNA and blood levels of dopamine were observed. Results: In EA group and salvia miltiorrhiza group, the expression of Hsp70 mRNA was higher and the content of dopamine was lower than those in control group(all P0 05); and the changes in EA+salvia miltiorrhiza group were more obvious than EA group and salvia miltiorrhiza group (both P0 05). Conclusion: EA and salvia miltiorrhiza can raise Hsp70 mRNA expression and inhibit the increase of dopamine content in blood after ischemia/reperfusion. There are synergistic actions between electroacupuncture and salvia miltiorrhiza." @default.
- W2367560769 created "2016-06-24" @default.
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- W2367560769 date "2004-01-01" @default.
- W2367560769 modified "2023-09-23" @default.
- W2367560769 title "Protective effect of electroacupuncture combined salvia miltiorrhiza(丹参)on ischemia/reperfusion myocardium" @default.
- W2367560769 hasPublicationYear "2004" @default.
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