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- W2367576912 abstract "Background/Aims: Gastric metaplasia (GM) is found in many patients with duodenal ulcer, and the recurrence of duodenal ulcer is likely to be associated with GM as well as H. pylori infection. This study was performed to evaluate the effect of H. pylori infection on histologic findings and IL-8 expression of the gastroduodenal mucosa including the area of GM in the patients with duodenal ulcer scar. Methods: Thirty patients with duodenal ulcer scar and nine volunteers with no gastroduodenal ulcer as control underwent gastroduodenoscopy with methylene blue spray and biopsies. The biopsy specimens were stained with H&E, Warthin-Starry, and alcian blue-PAS, and then measured their interleukin-8 expression (IL-8) by ELISA. Results: Control group had no GM. Thirty patients with duodenal ulcer scar showed GM. Among them, the grade of inflammation in patients with H. pylori infection was significantly higher than those without H. pylori infection (p" @default.
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- W2367576912 date "2002-01-01" @default.
- W2367576912 modified "2023-09-27" @default.
- W2367576912 title "Effect of Helicobacter pylori Infection on Mucosal Interleukin-8 Expression in Gastric Metaplasia" @default.
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