Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367579424> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2367579424 abstract "Objective To investigate the effect of insulin-like growth factor-1(IGF-1) on proliferation of human lens epithelial cells(LECs) in vitro.Methods Immortalized human lens epithelial B-3(HLEB-3)were cultured and passaged in this experiment.IGF-1 was added into the medium to obtain the terminal concentration at 5,10,20,30,40,50,60 μg·L-1 respectively.And HLEB-3 was exposed to different concentrations for different time points.Proliferation of HLEB-3 was detected with methyl thiazolyl tetrazolium(MTT) assay.The expression of α-actin in LECs was examined with Western blotting mothods.Results IGF-1 induced proliferation of HLEB-3 in 5 μg·L-1(P0.05),and proliferation of HLEB-3 was concentration-dependent.HLEB-3 treated by IGF-1 showed an increase in α-actin expression at protein levels.Proliferation of HLEB-3 line and the expression of α-actin protein in HLEB-3 was considerably increased with IGF-1 in experimental group compared with control group(P0.01),and the expression of α-actin protein increased with the IGF-1 concentration increasing.Conclusion IGF-1 can enhance proliferation of human LECs in vitro and play its role at concentration-dependent manner." @default.
- W2367579424 created "2016-06-24" @default.
- W2367579424 creator A5066183096 @default.
- W2367579424 date "2012-01-01" @default.
- W2367579424 modified "2023-09-25" @default.
- W2367579424 title "Effect of insulin-like growth factor-1 on proliferation of human lens epithelial cells in vitro" @default.
- W2367579424 hasPublicationYear "2012" @default.
- W2367579424 type Work @default.
- W2367579424 sameAs 2367579424 @default.
- W2367579424 citedByCount "0" @default.
- W2367579424 crossrefType "journal-article" @default.
- W2367579424 hasAuthorship W2367579424A5066183096 @default.
- W2367579424 hasConcept C104317684 @default.
- W2367579424 hasConcept C125705527 @default.
- W2367579424 hasConcept C151730666 @default.
- W2367579424 hasConcept C15336307 @default.
- W2367579424 hasConcept C153911025 @default.
- W2367579424 hasConcept C170493617 @default.
- W2367579424 hasConcept C185592680 @default.
- W2367579424 hasConcept C202751555 @default.
- W2367579424 hasConcept C2775960820 @default.
- W2367579424 hasConcept C2780689927 @default.
- W2367579424 hasConcept C54355233 @default.
- W2367579424 hasConcept C55493867 @default.
- W2367579424 hasConcept C62112901 @default.
- W2367579424 hasConcept C81885089 @default.
- W2367579424 hasConcept C85265743 @default.
- W2367579424 hasConcept C86803240 @default.
- W2367579424 hasConcept C95444343 @default.
- W2367579424 hasConceptScore W2367579424C104317684 @default.
- W2367579424 hasConceptScore W2367579424C125705527 @default.
- W2367579424 hasConceptScore W2367579424C151730666 @default.
- W2367579424 hasConceptScore W2367579424C15336307 @default.
- W2367579424 hasConceptScore W2367579424C153911025 @default.
- W2367579424 hasConceptScore W2367579424C170493617 @default.
- W2367579424 hasConceptScore W2367579424C185592680 @default.
- W2367579424 hasConceptScore W2367579424C202751555 @default.
- W2367579424 hasConceptScore W2367579424C2775960820 @default.
- W2367579424 hasConceptScore W2367579424C2780689927 @default.
- W2367579424 hasConceptScore W2367579424C54355233 @default.
- W2367579424 hasConceptScore W2367579424C55493867 @default.
- W2367579424 hasConceptScore W2367579424C62112901 @default.
- W2367579424 hasConceptScore W2367579424C81885089 @default.
- W2367579424 hasConceptScore W2367579424C85265743 @default.
- W2367579424 hasConceptScore W2367579424C86803240 @default.
- W2367579424 hasConceptScore W2367579424C95444343 @default.
- W2367579424 hasLocation W23675794241 @default.
- W2367579424 hasOpenAccess W2367579424 @default.
- W2367579424 hasPrimaryLocation W23675794241 @default.
- W2367579424 hasRelatedWork W1972822382 @default.
- W2367579424 hasRelatedWork W1978081956 @default.
- W2367579424 hasRelatedWork W1981471718 @default.
- W2367579424 hasRelatedWork W1996624229 @default.
- W2367579424 hasRelatedWork W1998672191 @default.
- W2367579424 hasRelatedWork W2002183152 @default.
- W2367579424 hasRelatedWork W2020494140 @default.
- W2367579424 hasRelatedWork W2030898174 @default.
- W2367579424 hasRelatedWork W2036406468 @default.
- W2367579424 hasRelatedWork W2036409857 @default.
- W2367579424 hasRelatedWork W2058271583 @default.
- W2367579424 hasRelatedWork W2071338484 @default.
- W2367579424 hasRelatedWork W2079639967 @default.
- W2367579424 hasRelatedWork W2293567006 @default.
- W2367579424 hasRelatedWork W2369134027 @default.
- W2367579424 hasRelatedWork W2376603797 @default.
- W2367579424 hasRelatedWork W2410818128 @default.
- W2367579424 hasRelatedWork W2416426743 @default.
- W2367579424 hasRelatedWork W2884633273 @default.
- W2367579424 hasRelatedWork W3151241512 @default.
- W2367579424 isParatext "false" @default.
- W2367579424 isRetracted "false" @default.
- W2367579424 magId "2367579424" @default.
- W2367579424 workType "article" @default.